DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH SOLUTE CARRIER FAMILY 22 MEMBER 6 LIKE 2 (SLC22A6-LIKE2)

摘要

The invention provides a human SLC22A6-like2 which is associated with the gastroenterological diseases, cancer (e.g. colon, lung tumor), hematological diseases, inflammation, respiratory diseases (e.g. lung COPD), muscle-skeleton diseases, neurological diseases and urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of gastroenterological diseases, cancer, hematological diseases, inflammation, respiratory diseases, muscle-skeleton diseases, neurological diseases and urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of SLC22A6-like2 as well as pharmaceutical compositions comprising such compounds.