发明名称 Enzyme activities and pH tests for the determination of the risk of obstetric and gynecologic complications in samples of body fluids of women
摘要 The current invention describes a method for selecting a particular population of women having a risk of developing obstetric or gynecologic pathologies indicated as odds ratio (OR) value higher than 5.5, comprising the following steps in order: a) determination of the levels of sialidase by means of the procedure described in Cauci et al. Am J Obstet Gynecol 1998; 178; 511-5 and/or prolidase activity by means of the procedure described in Cauci et al. J Infect Dis 1998; 178; 1698-706 in samples of body fluid; b) determination of the pH value of said body fluid samples; c) selecting the samples having a sialidase value equal or above 5.0 nmol of methoxyphenol and/or a prolidase level equal or above 1500 mOD for prolidase and a pH>=5.0. Consequently, this method gives the physician an efficient tool to decide whether or not to administer a pharmacological therapy to women at risk of severe adverse outcomes.
申请公布号 US2005095660(A1) 申请公布日期 2005.05.05
申请号 US20030698795 申请日期 2003.10.31
申请人 UNIBIO, S.R.I. 发明人 CAUCI SABINA
分类号 C12Q1/34;C12Q1/37;G01N33/68;(IPC1-7):C12Q1/34 主分类号 C12Q1/34
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