Biaryl compound and use thereof

摘要

The present invention provides a compound having melanocortin receptor agonist activity or antagonist activity, which is a novel biaryl compound represented by the formula (I): wherein ring A and ring B are optionally further substituted 6-membered aromatic rings; X is -CONR⁴-, -SO₂NR⁴-, -CH₂NR⁴- (R⁴ is a hydrogen atom, an optionally substituted hydrocarbon group, etc.), etc.; Y is a spacer having 1 to 12 atoms, etc.; Z is -CONR⁶-, -CO- (R⁶ is a hydrogen atom, an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group), etc.; R¹ is an optionally substituted amino group, etc.; R² is an optionally substituted hydrocarbon group, etc.; R³ is an optionally substituted hydrocarbon group, etc.; and R⁵ is an optionally substituted hydrocarbon group, etc.; or a salt thereof.