Methods and compositions for treating gastrointestinal tract mucin production associated disease conditions

摘要

The invention provides a method of treatment for an animal having a disease state associated with a mucus secretion disorder with a chloride channel modulator. The invention further provides for a method of screening for therapeutic compounds using the chloride channel. Also provided is a transgenic animal having a disrupted chloride gene, and a method of diagnosing a disease state associated with a mucus secretion disorder.