发明名称 |
Compositions and methods for producing vascular occlusion |
摘要 |
The present invention relates generally to methods and compositions for targeting, delivering, and activating platelet-dependent vascular occlusion agents. In particular, antibodies carrying platelet binding agents are targeted to hyperplastic cells or tissues, such as the vasculature of solid tumor masses; the platelet binding agent then binds and activates platelets, which in turn bind and activate other platelets. This process results in the formation of a platelet-mediated thrombus-causing vessel occlusion.
|
申请公布号 |
US6887474(B1) |
申请公布日期 |
2005.05.03 |
申请号 |
US19990438944 |
申请日期 |
1999.11.12 |
申请人 |
VIREXX MEDICAL CORPORATION |
发明人 |
STEWART MICHAEL WILLIAM;PERSON ROLAND HENRYK;NOUJAIM ANTOINE |
分类号 |
A61K31/727;A61K31/737;A61K35/14;A61K38/00;A61K38/36;A61K38/48;A61K38/55;A61K39/395;A61K45/06;A61K47/48;A61P7/04;A61P35/00;C07K16/28;C07K16/30;(IPC1-7):A61K39/395;A61K39/385;C07K14/435;C07K14/705 |
主分类号 |
A61K31/727 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|