发明名称 Compounds as dynamic organ function monitoring agents
摘要 Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume in vivo.
申请公布号 US6887854(B2) 申请公布日期 2005.05.03
申请号 US20030436759 申请日期 2003.05.13
申请人 MALLINCKRODT INC. 发明人 ACHILEFU SAMUEL;JIMENEZ HERMO N.;RAJAGOPALAN RAGHAVAN;DORSHOW RICHARD B.;BUGAI JOSEPH E.
分类号 C07H15/26;A61K49/00;C07D209/08;C07D209/12;C07D209/60;C07D405/14;(IPC1-7):A01N43/04;A61K31/70;C07H15/00;C07D277/04 主分类号 C07H15/26
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