| 发明名称 |
Method of preventing decrease in the activity of protein due to freezing and use of polypeptide in the production of protein activity decrease preventing agent |
| 摘要 |
An objective of the present invention is to provide a means to prevent freeze-induced decrease in protein activity. The present invention relates to a method for preventing freeze-induced decrease in protein activity comprising adding a polypeptide comprising the following amino acid sequence (I) to a protein to be frozen. Further, the present invention relates to use of a polypeptide comprising the following amino acid sequence (I) to produce an agent for preventing freeze-induced decrease in protein activity: <tables id="TABLE-US-00001" num="00001"> <table frame="none" colsep="0" rowsep="0" tabstyle="monospace"> <tgroup align="left" colsep="0" rowsep="0" cols="2"> <colspec colname="1" colwidth="217pt" align="right"/> <colspec colname="2" colwidth="0pt" align="left"/> <TBODY VALIGN="TOP"> <ROW> <ENTRY>(SEQ ID NO: 1)</ENTRY> <ENTRY/> </ROW> </TBODY> </TGROUP> <tgroup align="left" colsep="0" rowsep="0" cols="2"> <colspec colname="1" colwidth="217pt" align="left"/> <colspec colname="2" colwidth="0pt" align="left"/> <TBODY VALIGN="TOP"> <ROW> <ENTRY>Ser-Ser-Thr-Gly-Ser-X1-Ser-X2-Thr-Asp-X3-X4-X5-X6-</ENTRY> <ENTRY/> </ROW> <ROW> <ENTRY>X7-X8-Gly-Ser-X9-Thr-Ser-Gly-Gly-Ser-Ser-Thr-Tyr-</ENTRY> </ROW> <ROW> <ENTRY>Gly-Tyr-Ser-Ser-X10-X11-X12-X13-Gly-X14-Val (I).</ENTRY> </ROW> </TBODY> </TGROUP> </TABLE> </TABLES>
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| 申请公布号 |
US6887979(B2) |
申请公布日期 |
2005.05.03 |
| 申请号 |
US20020148306 |
申请日期 |
2002.05.29 |
| 申请人 |
SEIREN KABUSHIKI KAISHA |
发明人 |
NAKAMORI SHIGERU;TAKAGI HIROSHI;TAKAHASHI MASAKAZU;TSUJIMOTO KAZUHISA;YAMADA HIDEYUKI |
| 分类号 |
C07K14/435;C12N9/96;(IPC1-7):C07K1/00;C12P21/06;C12N9/00;C12N1/20;C12N15/00 |
主分类号 |
C07K14/435 |
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