Novel 3-substituted-androst-11-ones and processes for their preparation

摘要

Novel 3-substituted-androst-16-en-11-ones of the general formula wherein R represents hydrogen or an acyl radical are obtained by reacting a corresponding 3 - substituted - 16 - bromo - 17 - hydroxy-androstan-11-one with a reducing metal, e.g. zinc to give the desired 3-substituted-androst-16-en-11-one. Compositions having analgesic, anti-convulsant or tranquillizing activity and containing the above compounds are employed orally, trancutaneously or rectally.