发明名称 |
INHIBITORS OF CYCLIN-DEPENDENT KINASES, COMPOSITIONS AND USES RELATED THERETO |
摘要 |
The invention pertains to novel cyclin dependent kinase inhibitors (cdks) and specifically, but not exclusively, as inhibitors of cdk/cyclin complexes. As described herein, the inhibitors of this invention are capable of inhibiting the cell-cycle machinery and consequently may be useful in modulating cell-cycle progression, ultimately controlling cell growth and differentiation. Such compounds would be useful for treating subjects having disorders associated with excessive cell proliferation. |
申请公布号 |
PL369742(A1) |
申请公布日期 |
2005.05.02 |
申请号 |
PL20020369742 |
申请日期 |
2002.10.15 |
申请人 |
GPC BIOTECH INC.;GPC BIOTECH AG |
发明人 |
BOCKOVICH NICHOLAS;KLUGE ARTHUR F.;RAM SIYA;WANG ZHONGHUO;OALMANN CHRIS;MURTHI KRISHNA K.;BECKER FRANK |
分类号 |
A61K31/496;A61K31/522;A61K31/5377;A61K31/675;A61P17/14;A61P31/12;A61P31/18;A61P35/00;A61P43/00;C07D231/54;C07D403/12;C07D487/04;C07F9/6558;C07F9/6561;C40B30/04;G01N33/68 |
主分类号 |
A61K31/496 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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