| 发明名称 |
CATHEPSIN CYSTEINE PROTEASE INHIBITORS |
| 摘要 |
This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis. |
| 申请公布号 |
HRP20040800(A2) |
申请公布日期 |
2005.04.30 |
| 申请号 |
HR2004P000800 |
申请日期 |
2004.09.03 |
| 申请人 |
MERCK FROSST CANADA & CO. AXYS PHARMACEUTICALS |
发明人 |
CHRISTOPHER I. BAYLY;CAMERON BLACK;SERGE LEGER;CHUN-SING LI;DAN MCKAY;CHRISTOPHE MELLON;MICHAEL J. GREEN;BERNARD L. HIRSCHBEIN;JAMES W. JANC;JAMESPALMER JAMES T;CHITRA BASKARAN;JACQUES YVES GAUTHIER;CHEUK LAU;MICHEL THERIEN;VOUY-LINH TRUONG |
| 分类号 |
C07D295/12;A61K31/275;A61K31/381;A61K31/404;A61K31/417;A61K31/42;A61K31/4245;A61K31/426;A61K31/427;A61K31/44;A61K31/4406;A61K31/4409;A61K31/4465;A61K31/47;A61K31/495;A61K31/505;A61K31/5375;A61K45/00;A61P1/02;A61P3/14;A61P19/02;A61P19/08;A61P19/10;A61P29/00;A61P35/00;A61P43/00;C07C255/25;C07C255/29;C07C255/46;C07C255/58;C07C255/60;C07C259/10;C07C311/37;C07C317/32;C07C317/36;C07D209/08;C07D211/26;C07D211/38;C07D213/36;C07D213/38;C07D213/57;C07D213/61;C07D213/64;C07D213/70;C07D213/71;C07D213/74;C07D213/89;C07D215/12;C07D231/12;C07D233/54;C07D233/64;C07D239/06;C07D239/26;C07D241/12;C07D261/08;C07D263/32;C07D271/06;C07D277/28;C07D295/135;C07D295/22;C07D307/52;C07D333/20;C07D401/04;C07D417/04 |
主分类号 |
C07D295/12 |
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