发明名称 METHOD OF OBTAINING CITALOPRAM
摘要 Process for preparing purified citalopram or one of its salts that comprises the purification of citalopram by selective extractions of citalopram or of its impurities with organic solvents and water under specific conditions of pH and temperature. The crude citalopram can be prepared by a process that comprises making 1-Ä3-(dimethylamine)propylÜ-1-(4-fluorophenyl)-1,3-dihydro-5-bromoisobenzofuran react with copper cyanide.
申请公布号 HRP20040622(A2) 申请公布日期 2005.04.30
申请号 HR2004P000622 申请日期 2004.07.08
申请人 ESTEVE QUIMICA S.A. 发明人 LAURA COPPI;YOLANDA GASANZ GUILLEN;JULIO CAMPON PARDO
分类号 C07D307/87 主分类号 C07D307/87
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