| 摘要 |
A pharmaceutical composition comprising orlistat and a bile acid sequestrant selected from cholestyramine, colestipol, coleselevam, colestimide, sevelamer, cellulose derivates, dextran derivatives, starch and starch derivatives is described. The composition is useful for the treatment or prevention of obesity. The bile acid sequestrant can be used in the manufacture of medicament for the treatment or prevention of gastrointestinal side effects selected from oily spotting, fatty/oily stools, fecal urgency, increased defecation and fecal incontinence. |
