SULFOXIMINE-SUBSTITUTED PYRIMIDINES AS CDK AND/OR VEGF INHIBITORS, THEIR PRODUCTION AND USE AS PHARMACEUTICAL AGENTS

摘要

The present invention relates to the pyrimidine derivatives of formula (I),
wherein Q, R1, R2, R3, R4, R5, X, and m are defined as in the description, for
use as inhibitors of cyclin-dependent kinases and VEGF receptor
tyrosinkinases. The invention also relates to a method for producing the same
and to the use of the inventive pyrimidines as drugs in the treatment of
various diseases.