SMALL PARTICLE AEROSOL LIPOSOMES FOR DELIVERY OF ANTI-CANCER DRUGS
摘要
Provided herein is a method of treating primary long cancer or metastatic cancer to the long in an individual by delivering at least once to the respiratory tract of the individuai via inhalation a nebulized liposomal aerosol comprising a dilauroylphosphatidylcholine liposome containing camptothecin or a derivative thereof in an amount sufficient to deliver a pharmacologically effective dose of the camptothecin or its derivative to treat the cancer. Also provided is a nebulized liposomal aerosol comprising the DLPC containing the camptothecin or its derivative and a method of making the liposome-drug comprising the aerosol.
申请公布号
WO2005037341(A2)
申请公布日期
2005.04.28
申请号
WO2004US29823
申请日期
2004.09.14
申请人
RESEARCH DEVELOPMENT FOUNDATION;KNIGHT, VERNON, J.;KOSHKINA, NADEZHDA;GILBERT, BRIAN;VERSCHRAEGEN, CLAIRE, F.
发明人
KNIGHT, VERNON, J.;KOSHKINA, NADEZHDA;GILBERT, BRIAN;VERSCHRAEGEN, CLAIRE, F.