摘要 |
A class of benzopyrans and analogs thereof is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula (I''): wherein X, A<1>, A<2>, A3, A<4>, R, R'', R<1> and R<2> are as described in the specification.
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申请人 |
G.D. SEARLE &CO. |
发明人 |
CARTER, JEFFREY, S.;DEVADAS, BALEKUDRU;TALLEY, JOHN, J.;BROWN, DAVID, L.;GRANETO, MATHEW, J.;ROGIER, DONALD, J., JR.;NAGARAJAN, SRINIVASAN, R.;HANAU, CATHLEEN, E.;HARTMANN, SUSAN, J.;LUDWIG, CINDY, L.;METZ, SUZANNE;KORTE, DONALD, E.;BERTENSHAW, STEPHEN, R.;OBUKOWICZ, MARK, G. |