| 摘要 |
The invention relates to a molecular probe (MS) for detecting an analyte (AN), comprising: a basic structure (GS); at least two groups of detectors (D1, D2) that are directly or indirectly bound to the basic structure (GS) and can simultaneously interact with the analyte (AN); at least two groups of signals (S1, S2) which are directly or indirectly bound to the basic structure (GS); at least one signaling conformation of the molecular probe (MS), in which the groups of signals (S1, S2) interact with each other in such a way that a detectable signal is generated; and at least one mute conformation in which the detectable signal is not generated. The inventive probe combines the functions required for detecting an analyte, i.e. detection, signal transduction, and signal generation, and can be easily adapted to different detection problems as a result of the modular structure thereof. |
