REACTION MONITORING OF CHIRAL MOLECULES USING FOURIER TRANSFORM INFRARED VIBRATIONAL CIRCULAR DICHROISM SPECTROSCOPY
摘要
<p>A method and apparatus to monitor the enantiomeric excess of chiral molecules participating in a chemical reaction. The method includes real time monitoring of the chemical reaction by obtaining a VCD spectra and an IR spectra of the chemical compounds in the reaction, and manipulating the spectra to obtain a % EE value. Using such real time information, the reaction parameters can be changed to shift the reaction to produce more of one chiral molecule than another.</p>
申请公布号
WO2005038439(A1)
申请公布日期
2005.04.28
申请号
WO2004US34427
申请日期
2004.10.13
申请人
BIO TOOLS, INC.;NAFIE, LAWRENCE, A.;GUO, CHANGNING;DUKOR, RINA, K.
发明人
NAFIE, LAWRENCE, A.;GUO, CHANGNING;DUKOR, RINA, K.