HIGH THROUGHPUT SCREENING OF APTAMER LIBRARIES FOR SPECIFIC BINDING TO PROTEINS ON VIRUSES AND OTHER PATHOGENS

摘要

The present invention includes composition and methods for making and using a combinatorial library to identify thioaptamers that bind to targets on or about pathogens. Compositions, kits and methods are also provided for the identification of pathogens, e.g., viral, bacterial or other proteins related infectious disease, as well as, vaccines and vaccine adjuvants are provided that modify host immune responses.