发明名称 |
Compositions of stabilized DNA for coating microprojctions |
摘要 |
The present invention provides methods and compositions for stabilizing dried nucleic acids with carbohydrates such as non-reducing sugars, polysaccharides, and reducing sugars. Preferably, the stabilized nucleic acids are coated on a microprojection member for transdermal delivery. The invention further provides compositions and methods that involve the use of DNase inhibitors to stabilize dried nucleic acids delivered directly into bodily tissues.
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申请公布号 |
US2005090009(A1) |
申请公布日期 |
2005.04.28 |
申请号 |
US20040972230 |
申请日期 |
2004.10.21 |
申请人 |
CORMIER MICHEL J.;WIDERA GEORG;AMERI MAHMOUD |
发明人 |
CORMIER MICHEL J.;WIDERA GEORG;AMERI MAHMOUD |
分类号 |
A61K48/00;C12N15/89;(IPC1-7):A61K48/00;C12N15/87 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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