A NOVEL USE OF RILUZOLE FOR TREATING RETINOPATHY

摘要

The present invention relates to riluzole and its similar benzthiazole family compounds for treating retinopathy. Riluzole can not only effectively inhibits the endothelial growth stimulated by vascular endothelial growth factor (VEGF) in the culture of endothelial cells, but also inhibit abnormal vascular formation in the mouse model of retinopathy of prematurity (ROP), thus being able to apply to ischemic or proliferative retinopathies such as diabetic retinopathy, arteriosclerosis of the retina, and ROP. As such, the present invention aims to provide riluzole in treating neovascular proliferative retinopathy.