发明名称 |
hG-CSF fusion polypeptide having c-mpl activity, DNA coding for same and methods of treating anemia using same |
摘要 |
The present invention relates to a fusion polypeptide which comprises a polypeptide having G-CSF activity and a polypeptide having TPO activity and DNA which codes for the fusion polypeptide, to a fusion polypeptide in which a polypeptide having G-CSF activity and a polypeptide having TPO activity are fused via a spacer peptide and DNA which codes for the fusion polypeptide and to a polypeptide in which the fusion polypeptide comprising a polypeptide having G-CSF activity and a polypeptide having TPO activity is chemically modified with a polyalkylene glycol derivative. It also relates to an anemia-treating composition containing the fusion polypeptide as an active ingredient.
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申请公布号 |
US6884419(B1) |
申请公布日期 |
2005.04.26 |
申请号 |
US20000680514 |
申请日期 |
2000.10.06 |
申请人 |
KYOWA HAKKO KOGYO, CO., LTD. |
发明人 |
YOKOI HARUHIKO;SHIOTSU YUKIMASA;KONISHI NOBORU;ANAZAWA HIDEHARU;TAMAOKI TATSUYA;YAMASAKI MOTOO;KATO YOKO;UCHIDA KAZUHISA;YAMASHITA KINYA |
分类号 |
A61K38/00;C07K14/52;C07K14/535;(IPC1-7):A61K38/19 |
主分类号 |
A61K38/00 |
代理机构 |
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主权项 |
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地址 |
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