NOVEL COMBINATION OF GLUCOCORTICOIDS AND PDE-4-INHIBITORS FOR TREATING RESPIRATORY DISEASES, ALLERGIC DISEASES, ASTHMA AND COPD.

摘要

The invention relates to a novel combination of a glucocorticoid, especially loteprednol, and at least one phosphodiesterase-4 inhibitor (PDE-4-inhibitor), especially hydroxyindole-derivative N-(3, 5- dichloropyridine -4-yl)-2 -[1-(4- fluorbenzyl)-5 -hydroxyindole -3-yl]-2 -oxoacetamide, for a simultaneous, sequential or separate administration in the treatment of respiratory diseases, allergic diseases, asthma and chronic obstructive pulmonary diseases (COPD).