摘要 |
<P>PROBLEM TO BE SOLVED: To provide a sendai virus vector sufficiently available in the field of gene therapy and the like by establishing a sendai virus reconstitution system with good manufacturing efficiency and enabling gene manipulation of the sendai virus. <P>SOLUTION: A method for reconstituting sendai virus particles by introducing a sendai virus genome into a host cell expressing all initial replication genes is developed. Gene manipulation of the sendai virus thereby allows to effectively use the sendai virus as a vector. <P>COPYRIGHT: (C)2005,JPO&NCIPI |