发明名称 |
Method for generating recombinant human platelets for identifying therapeutic target proteins |
摘要 |
A composition is provided comprising patelets having a combination of the following modifications: a) a modification of the protein constituents of the platelets which is obtained or obtainable by genetic modification of platelet precursor cells; b) incorporation of a detectable label into said platelet; whereby the functions of modification a) and b) are mutually independent. Further, methods of determining platelet functions, notably aggregation and adhesion to endothelial cells are provided. Further, a novel method of preparing transgenic or modified platelets is provided.
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申请公布号 |
US2005086710(A1) |
申请公布日期 |
2005.04.21 |
申请号 |
US20040503785 |
申请日期 |
2004.08.06 |
申请人 |
PELUSO MARIO;UNGERER MARTIN;GAWAZ MEINRAD;MASSBERG STEFFEN;LAUGWITZ KARL-LUDWIG;GILLITZER ANGELIKA |
发明人 |
PELUSO MARIO;UNGERER MARTIN;GAWAZ MEINRAD;MASSBERG STEFFEN;LAUGWITZ KARL-LUDWIG;GILLITZER ANGELIKA |
分类号 |
C12N5/078;G01N33/50;(IPC1-7):A01K67/027 |
主分类号 |
C12N5/078 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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