发明名称 |
Novel alkansulfonamides as endothelin antagonists |
摘要 |
The invention relates to novel alkansulfonamides of structure (I), wherein R<SUP>1 </SUP>is a lowel alzyl group and the other variables are as defined in the description, and their use as active ingredients in the preparation of pharmaceutical compositions. The invention aslo concerns related aspects inluding processes for the preparation of the compounds, pharmaccutical compositions containing one or more of those compounds and especially their use as endothelin receptor antagonists in the treatment and prevention of diseases associated to the endothelin system.
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申请公布号 |
US2005085639(A1) |
申请公布日期 |
2005.04.21 |
申请号 |
US20040500485 |
申请日期 |
2004.06.29 |
申请人 |
BOLLI MARTIN;BOSS CHRISTOPH;CLOZEL MARTINE;FISCHLI WALTER;WELLER THOMAS |
发明人 |
BOLLI MARTIN;BOSS CHRISTOPH;CLOZEL MARTINE;FISCHLI WALTER;WELLER THOMAS |
分类号 |
C07D239/47;A61K31/506;A61K31/5377;A61P1/04;A61P7/00;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P13/12;A61P15/00;A61P15/10;A61P25/00;A61P25/06;A61P25/28;A61P27/06;A61P27/16;A61P29/00;A61P31/04;A61P35/00;A61P43/00;C07D239/46;C07D239/52;C07D239/54;C07D239/545;C07D239/56;C07D401/04;C07D401/14;C07D403/04;C07D403/14;(IPC1-7):C07D43/02 |
主分类号 |
C07D239/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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