| 发明名称 |
Benzamide derivatives, processes for their preparation, and their pharmaceutical use |
| 摘要 |
The present invention relates to novel hydroxyethylene compounds having Asp2 (beta-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated beta-amyloid levels or beta-amyloid deposits, particularly Alzheimer's disease.
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| 申请公布号 |
US2005085520(A1) |
申请公布日期 |
2005.04.21 |
| 申请号 |
US20040496269 |
申请日期 |
2004.10.29 |
| 申请人 |
FALLER ANDREW;MACPHERSON DAVID T.;MILNER PETER H.;STANWAY STEVEN J.;TROUW LEONTINE S. |
发明人 |
FALLER ANDREW;MACPHERSON DAVID T.;MILNER PETER H.;STANWAY STEVEN J.;TROUW LEONTINE S. |
| 分类号 |
A61K31/402;A61K31/4025;A61K31/421;A61K31/4439;A61K31/451;A61K31/55;A61P9/00;A61P25/16;A61P25/28;A61P43/00;C07D207/26;C07D207/267;C07D207/27;C07D211/76;C07D223/10;C07D263/20;C07D263/22;C07D401/04;(IPC1-7):A61K31/426;A61K31/416 |
主分类号 |
A61K31/402 |
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