发明名称 |
COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS |
摘要 |
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, BCR-Abl, CSK, JNK1, JNK2, PDGF-R, p38, p70S6K, TGF beta , SRC, EGFR, c-Kit, trkB, FGFR3, Fes, Lck, Syk, RAF, MKK4, MKK6 and SAPK2 beta kinases. |
申请公布号 |
WO2005034869(A2) |
申请公布日期 |
2005.04.21 |
申请号 |
WO2004US33009 |
申请日期 |
2004.10.08 |
申请人 |
IRM LLC;DING, QIANG;XIE, YONGPING;GRAY, NATHANAEL SCHIANDER;YOU, SHULI;CHOPIUK, GREG;JIANG, JIQING;LIU, YI;STEENSMA, RUO;WANG, XING;SIM, TAEBO |
发明人 |
DING, QIANG;XIE, YONGPING;GRAY, NATHANAEL SCHIANDER;YOU, SHULI;CHOPIUK, GREG;JIANG, JIQING;LIU, YI;STEENSMA, RUO;WANG, XING;SIM, TAEBO |
分类号 |
A61K;A61K31/44;A61K31/47;A61K31/4706;A61K31/4745;A61K31/519;C07D215/16;C07D471/00;C07D471/02 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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