发明名称 Novel 3-aryl-2,5-dihydroxy-1,4-benzoquinone derivatives, their preparation method and pharmaceutical compositions containing same
摘要 Compound of formula (I): wherein: R<SUB>1 </SUB>and R<SUB>2</SUB>, which may be identical or different, each represents hydrogen, acyl or alkyl, Ar represents aryl or heteroaryl, A represents a group selected from: R<SUB>4 </SUB>represents hydrogen or alkyl, R<SUB>5 </SUB>represents hydrogen, alkyl, aryl or heteroaryl, R<SUB>3 </SUB>represents aryl, heteroaryl, dicyclopropylmethyl or benzhydryl, or A-R<SUB>3 </SUB>represents an optionally substituted naphthyl group, with the exclusion of 2,5-dihydroxy-3-(4-methoxyphenyl)-6-(2-phenylethenyl)-1,4-benzoquinone, 2,5-dihydroxy-3-(4-methoxyphenyl)-6-(2-naphthyl)-1,4-benzoquinone and 2,5-dihydroxy-3-(2-naphthyl)-6-phenyl-1,4-benzoquinone. Medicinal products containing the same which are useful in the treatment of diseases associated with a deregulation of glycaemia.
申请公布号 US2005085644(A1) 申请公布日期 2005.04.21
申请号 US20040503527 申请日期 2004.08.04
申请人 DASSONVILLE ALEXANDRA;BRETECHE ANNE;DUFLOS MURIEL;LE BAUT GUILLAUME;PFEIFFER BRUNO;RENARD PIERRE;LEVENS NIGEL;HUSSON-ROBERT BERNADETTE 发明人 DASSONVILLE ALEXANDRA;BRETECHE ANNE;DUFLOS MURIEL;LE BAUT GUILLAUME;PFEIFFER BRUNO;RENARD PIERRE;LEVENS NIGEL;HUSSON-ROBERT BERNADETTE
分类号 A61K31/122;A61K31/222;A61K31/4402;A61P3/10;C07C45/00;C07C45/28;C07C46/00;C07C46/10;C07C50/28;C07C50/30;C07D213/50;(IPC1-7):C07C50/38;C07D213/46;C07D207/00 主分类号 A61K31/122
代理机构 代理人
主权项
地址