The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. In accordance with the present invention, a selectable marker gene has been recombinantly targeted to the brachyury locus to allow the isolation and characterization of cell populations that comprise brachyury positive mesendoderm and mesoderm cells. The cell populations of the invention are useful for generating cells for cell replacement therapy.
申请公布号
WO2004098490(A3)
申请公布日期
2005.04.21
申请号
WO2003US15658
申请日期
2003.05.19
申请人
MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY;KELLER, GORDON, M.;KOUSKOFF, VALERIE;KUBO, ATSUSHI;FEHLING, HANS, JOERG
发明人
KELLER, GORDON, M.;KOUSKOFF, VALERIE;KUBO, ATSUSHI;FEHLING, HANS, JOERG
