Process for producing 2-alkyl-3-amidothiophene derivative

摘要

The present invention provides a method for reducing a sulfur-containing compound by hydrogenation using a noble metal catalyst. The present invention also provides an industrial method for producing a 2-alkyl-3-aminothiophene derivative with high economical efficiency by hydrogenating a 2-alkenyl-3-aminothiophene derivative using the noble metal catalyst. 2-Alkyl-3-aminothiophene derivatives are useful compounds in the fields of medicine and agriculture, and in particular, useful in bactericides for agriculture or gardening, or intermediates of the bactericides. <??>For example, in the production of a 2-alkyl-3-aminothiophene derivative by hydrogenating a 2-alkenyl-3-aminothiophene derivative using a noble metal catalyst, the reaction temperature is controlled at 150 DEG C to 300 DEG C. This method allows the used noble metal catalyst to be recovered and reused. <??>In the present invention, a sulfur-containing compound is reduced by hydrogenation at a reaction temperature of 150 DEG C to 300 DEG C using a noble metal catalyst to recover and reuse the noble metal catalyst. The method of the present invention is useful as an industrial reducing method by hydrogenation.