发明名称 АГЕНТЫ, УВЕЛИЧИВАЮЩИЕ АФФИННОСТЬ
摘要 This invention relates to a kit containing a multivalent, multi-specific binding protein and a carrier molecule. The binding protein has two or more binding sites where at least one binding site binds with a hapten moiety and at least one site binds with a target antigen. The carrier molecule contains a linking molecule that bears a diagnostic agent and/or a therapeutic agent and two or more haptens. The present invention further relates to bispecific diabodies that bind with hapten moieties and target antigens and to recombinant vectors useful for the expression of these-functional diabodies in a microbial host.
申请公布号 RU2004114878(A) 申请公布日期 2005.04.20
申请号 RU20040114878 申请日期 2002.10.15
申请人 ИММУНОМЕДИКС, ИНК. (US);АйБиСи ФАРМАСЬЮТИКАЛЗ (US) 发明人 ЧАНГ Чиен-Хсинг Кен (US);РОССИ Эдмунд (US)
分类号 C12N15/09;A61K38/00;A61K38/02;A61K38/22;A61K39/395;A61K45/00;A61K45/06;A61K47/42;A61K47/48;A61P9/00;A61P29/00;A61P31/00;A61P35/00;A61P37/06;C07K2/00;C07K16/18;C07K16/30;C07K16/32;C07K16/44;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/02;C12Q1/68 主分类号 C12N15/09
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