发明名称 СПОСОБ ПОЛУЧЕНИЯ 2-[5-(4-ФТОРФЕНИЛ)-3- ПИРИДИЛМЕТИЛАМИНОМЕТИЛ]ХРОМАНА
摘要 The present invention relates to a process for the preparation of 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chroman, the enantiomers and its salts, characterised in that 5-(4-fluorophenyl)pyridine-3-carbaldehyde is reacted directly with aminomethylchroman or its salts under reducing conditions to give 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chroman, and the latter is, if desired, converted into one of its physiologically acceptable salts by treatment with an acid.
申请公布号 RU2003132433(A) 申请公布日期 2005.04.20
申请号 RU20030132433 申请日期 2002.04.08
申请人 МЕРК ПАТЕНТ ГМБХ (DE) 发明人 Хайнц-Германн БОКЕЛЬ (DE);Штеффен НОЙНФЕЛЬД (DE);Лудвиг ГАНТЦЕРТ (DE);Ральф КНИРИМЕ (DE);Эльке ЗИМОН (DE);Ральф ДЕФАНТ (DE);Удо ХЕЛЬМ (DE);Хельмут РОЙБОЛЬД (DE)
分类号 C07D311/58;C07D405/12 主分类号 C07D311/58
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