LIPOPEPTIDES INDUCING T LYMPHOCYTIC CYTOTOXICITY BEARING AT LEAST ONE AUXILIARY T EPITOPE, AND USES FOR VACCINATION

摘要

The invention concerns lipopeptides comprising at least one auxiliary T epitope, at least one CTL epitope and at least a lipid residue, characterised in that the epitopes and the lipid part, and the epitopes are independently separated by amino acids, called spacers, comprising amino acid chains charged in neutral medium, ensuring affinity for water of said lipopeptides. The invention also concerns the use of said lipopeptides for inducing an immune response against HIV and BHV, papillo mavirus, melanoma p-53, or malaria.