发明名称 |
ПЕРОРАЛЬНЫЕ ПЕДИАТРИЧЕСКИЕ КОМПОЗИЦИИ ТРИМЕТОБЕНЗАМИДА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ |
摘要 |
Oral trimethobenzamide compositions and methods for treating and controlling nausea and/or vomiting are disclosed in warm blooded animals, especially humans including children. The oral trimethobenzamide compositions and methods of the present invention are at least as effective as a 200 mg intramuscular (I.M.) trimethobenzamide HCl injectable formulation. In addition, an oral composition containing about 300 mg of trimethobenzamide HCl is uniquely approximately bioequivalent to a 200 mg intramuscular (I.M.) trimethobenzamide HCl injectable formulation. The oral pediatric trimethobenzamide compositions and methods of the present invention are believed to be at least as effective as a 200 mg intramuscular (I.M.) trimethobenzamide HCl injectable formulation when administered at a dose of about 100 mg. In addition, an oral pediatric composition containing about 120 mg of trimethobenzamide HCl is believed to be uniquely approximately bioequivalent to a 200 mg intramuscular (I.M.) trimethobenzamide HCl injectable formulation when administered at a dose of about 100 mg. |
申请公布号 |
RU2004126685(A) |
申请公布日期 |
2005.04.20 |
申请号 |
RU20040126685 |
申请日期 |
2003.02.06 |
申请人 |
КИНГ ФАРМАСЬЮТИКАЛЗ, ИНК. (US) |
发明人 |
ГРЕГОРИ Джеефферсон Дж (US);БРАНС Роберт Дж (US);СИРОТТА Дин Р (US);РОДЖЕРС Томас К III (US);ПЭМПЛИН Чарльз Л III (US) |
分类号 |
A61K9/14;A61K9/00;A61K9/20;A61K9/48;A61K31/165;A61K31/166;A61K47/12;A61K47/26;A61K47/36;A61P1/08;A61P1/12 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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