8-SUBSTITUIERTE 2,6-METHANO-3-BENZAZOCINE UND 3- SUBSTITUIERTE MORPHINANE ALS OPIOIDREZEPTORBINDENDE AGENZIEN

摘要

8-Substituted-2,6-methano-3-benzazocines of general structure I in which A is—CH2—OH,—CH2NH2,—NHSO2CH3, and Y is O, S or NOH are useful as analgesics, anti-diarrheal agents, anticonvulsants, antitussives and anti-addiction medications. 8-Carboxamides, thiocarboxamides, hydroxyamidines and formamides are preferred.