发明名称 ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS
摘要 The invention relates to a compound having general formula (I), wherein: n represents an integer of between 1 and 6; A is selected from one or more X, Y and/or Z groups; X represents an optionally-substituted C1-2-alkylene group; Y represents an optionally-substituted C2-alkenylene group or a -C<u>=</u>C- group; Z represents a C3-7-cycloalkyl group having formula (II) in which m represents an integer of between 1 and 5, and p and q represent integers and are defined such that p+q equals a number of between 1 and 5; R1 represents a hydrogen atom, a halogen atom or a hydroxyl, cyano, nitro, C1-3-alkyl, C1-3-alkoxy, C1-3-thioalkyl, C1-3-fluoroalkyl, C1-3-fluoroalkoxy, C1-3-fluorothioalkyl group; R2 represents a hydrogen atom, a halogen atom or a cyano, nitro, hydroxyl, C1-3-alkyl, C1-3-alkoxy, C1-3-thioalkyl, C1-3-fluoroalkyl, C1-3-fluoroalkoxy, C1-3-fluorothioalkyl group, or an optionally-substituted aromatic or heteroaromatic group; R3 represents either a 2,2,2-trifluoroethyl group or an optionally-substituted phenyl group; and R6 and R7 represent independently of each other a C1-3-alkyl group, a phenyl; said compound taking the form of a base, an acid addition salt, a hydrate or a solvate. The invention also relates to the use of the compound in therapeutics.
申请公布号 WO2005033066(A2) 申请公布日期 2005.04.14
申请号 WO2004FR02486 申请日期 2004.10.01
申请人 SANOFI-AVENTIS;ABOUABDELLAH, AHMED;ALMARIO GARCIA, ANTONIO 发明人 ABOUABDELLAH, AHMED;ALMARIO GARCIA, ANTONIO
分类号 C07C271/12;C07C271/44;C07C271/48 主分类号 C07C271/12
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