发明名称 |
MODULATION OF GASTROINTESTINAL EPITHELIUM PROLIFERATION THROUGH THE WNT SIGNALING PATHWAY |
摘要 |
<p>These results indicate the efficacy of systemic expression of secreted Wnt antagonists as a general strategy for conditional inactivation of Wnt signaling in adult organisms, and illustrate a striking reliance on a single growth factor pathway for the maintenance of the architecture of the adult small intestine and colon. These results also indicate the potential utility of administration of Wnt pathway agonists for mucosal repair of the small intestine or colon.</p> |
申请公布号 |
WO2005032574(A1) |
申请公布日期 |
2005.04.14 |
申请号 |
WO2004US32666 |
申请日期 |
2004.10.04 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;KUO, CALVIN, JAY |
发明人 |
KUO, CALVIN, JAY |
分类号 |
A61K9/24;A61K9/64;A61K38/16;A61K38/17;A61K48/00;(IPC1-7):A61K38/00 |
主分类号 |
A61K9/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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