发明名称 |
METHOD FOR MONITORING REACTIONS IN REAL TIME |
摘要 |
Methods for monitoring chemical reactions in real time are provided. The methods involve the use of a signaling aptamer that has a different affinity for the substrate and the product of the chemical reaction. The conversion from substrate to product is detected as a change in signal, in particular a change in fluorescent signal. The methods of the present invention are also useful to measure enzyme activity and to screen for enzyme inhibitors. |
申请公布号 |
WO2005003377(A3) |
申请公布日期 |
2005.04.14 |
申请号 |
WO2004CA00966 |
申请日期 |
2004.06.29 |
申请人 |
MCMASTER UNIVERSITY;LI, YINGFU;NUTIU, RAZVAN |
发明人 |
LI, YINGFU;NUTIU, RAZVAN |
分类号 |
C12Q1/34;C12Q1/42;C12Q1/44;C12Q1/48;(IPC1-7):C12Q1/34 |
主分类号 |
C12Q1/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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