发明名称 |
SENSOR WITH INCREASEED BIOCOMPATIBILITY |
摘要 |
Sensors and methods for producing them are disclosed. A cavity is created and filled with a reagent that includes a conductive matrix, enzyme, catalyst, and binding agent, in a preferred embodiment. The cavity is substantially enclosed, leaving enough of an opening to allow the sample to enter. A portion of the material surrounding the cavity is preferably permeable to a substance useful for measuring reaction, but not to the reagent or the sample. Cavities that have the shape of a cone, conical frustum, pyramidal frustum, and right circular cylinder are given as examples. Other systems include a membrane that contains the sensor's active area and defines an internal volume of fluid, where the membrane or internal volume has a particular geometric relationship to the active area. |
申请公布号 |
WO2005032362(A2) |
申请公布日期 |
2005.04.14 |
申请号 |
WO2004US32293 |
申请日期 |
2004.09.30 |
申请人 |
ROCHE DIAGNOSTICS GMBH;F.HOFFMANN-LA ROCHE AG;MANG, ANDRE;BUCK, HARVEY, B.;GARRISON, MICHAEL D.;JERNIGAN, WALTER |
发明人 |
MANG, ANDRE;BUCK, HARVEY, B.;GARRISON, MICHAEL D.;JERNIGAN, WALTER |
分类号 |
A61B5/00;C12Q1/00 |
主分类号 |
A61B5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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