发明名称 IMIDAZOPYRIDINE SUBSTITUTED TROPANE DERIVATIVES WITH CCR5 RECEPTOR ANTAGONIST ACTIVITY FOR THE TREATMENT OF HIV AND INFLAMMATION
摘要 <p>The present invention provides compounds of formula (I) wherein R&lt;1&gt; and R&lt;2&gt; are as defined hereinabove. The compounds of the present invention are modulators, especially antagonists, of the activity of chemokine CCR5 receptors. Modulators of the CCR5 receptor may be useful in the treatment of various inflammatory diseases and conditions, and in the treatment of infection by HIV and genetically related retroviruses.</p>
申请公布号 WO2005033107(A1) 申请公布日期 2005.04.14
申请号 WO2004IB03153 申请日期 2004.09.28
申请人 GB;GB;US 发明人 STUPPLE, PAUL, ANTHONY
分类号 A61K31/4745;A61P31/18;C07D471/02;C07D519/00;(IPC1-7):C07D471/04;A61K31/418 主分类号 A61K31/4745
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