NEW BENZOINDOLINE COMPOUND, METHOD FOR PRODUCING THE SAME,AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

摘要

PROBLEM TO BE SOLVED: To produce a pharmaceutical of anα2-AR/5-HT2Cdual antagonist. SOLUTION: A compound expressed by formula (I) [R1and R2together form a benzo ring (which is optionally substituted by a halogen, an alkyl, an alkoxy, cyano, nitro, hydroxy, amino, an alkylamino, a dialkylamino or trifluoromethyl); and R3and R4are each H], its addition salt with a pharmaceutically acceptable acid or base, and a pharmaceutical are provided, respectively. COPYRIGHT: (C)2005,JPO&NCIPI