| 摘要 |
The synthesis of novel diketopiperazines, their use in inhibiting cellular events such as those involving NFK-alpha, NFK-beta and in the treatment of inflammation events, a combinatorial library of diverse diketopiperazines and process for their synthesis as a library and as individual compounds. In particular novel diketopiperazines are disclosed including their synthesis and use in cellular events such as activation of the transcription factor, nuclear factor, TNF-alpha, TNF-beta and also apoptosis.
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