TREATMENT OF INFLAMMATION

摘要

The invention provides use of an effective amount of a serine protease inhibitor selected from the group consisting of alpha 1-antitrypsin, secretory leucocyte protease inhibitor, C-reactive protein, serum amyloid A protein and alpha 2-macroglobulin, and pharmaceutically-acceptable salts thereof, for the prophylaxis or direct treatment of a mast cell-implicated disease or injury in a mammal. A pharmaceutical composition is also provided, comprising a serine protease inhibitor as listed above, for treatment of a patient suffering from a mast cell-implicated disease.