发明名称 |
MATRIX FOR SUSTAINED-RELEASE PREPARATION |
摘要 |
The present invention relates to a matrix for sustained-release preparation comprising an ester formed at a terminal carboxyl group of a straight-chain polyester which essentially consists of an .alpha.-hydroxymonocarboxylic acid. The matrix is stable to light, heat, moisture, coloring etc., and is of low toxicity. The sustained-release preparation produced by using the ester of the present invention offers stable drug release over an extended period of time, ensuring sustained stable effect. Furthermore, the sustained-release preparation does not show excess drug release just after administration.
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申请公布号 |
CA2143044(C) |
申请公布日期 |
2005.04.12 |
申请号 |
CA19952143044 |
申请日期 |
1995.02.21 |
申请人 |
WAKO PURE CHEMICAL INDUSTRIES LTD.;TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
IGARI, YASUTAKA;SAIKAWA, AKIRA;OKAMOTO, KAYOKO;KAMEI, SHIGERU;OKA, MASAHISA;SANO, ATSUNORI |
分类号 |
A61K9/16;C08G63/06;(IPC1-7):C08G63/91;A61K38/09;A61K38/19;A61K47/34 |
主分类号 |
A61K9/16 |
代理机构 |
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