发明名称 |
PROCESS FOR PREPARING HEPATITIS A (HAV) ANTIGENS AND VACCINES |
摘要 |
Process for preparing hepatitis A (HAV) antigens and vaccines. The HAV virus is multiplied on competent cells, the infected cells are lysed, the supernatant is recovered and the purification is carried out by a chromatographic procedure on an anion-exchange support and a gel filtration procedure, the purification procedures being carried out in the presence of a detergent, and the chromatographic procedure being carried out under conditions which retain the virions or viral capsids, which are then eluted.
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申请公布号 |
CA2108292(C) |
申请公布日期 |
2005.04.12 |
申请号 |
CA19932108292 |
申请日期 |
1993.10.13 |
申请人 |
PASTEUR MERIEUX SERUMS ET VACCINS |
发明人 |
FANGET, BERNARD;FRANCON, ALAIN |
分类号 |
A61K39/00;A61K38/00;A61K39/29;A61P1/16;A61P31/14;C07K14/10;(IPC1-7):C12N7/04 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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