发明名称 |
LYSOSOMAL ENZYME-CLEAVABLE ANTITUMOR DRUG CONJUGATES |
摘要 |
The present invention relates to drug-ligand conjugates wherein the drug is linked to the ligand through a protein peptide linker and a connector, a process for the preparation of said conjugates, method of controlling the growth of undesirable cells, pharmaceutical compositions, and intermediates thereof.
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申请公布号 |
CA2123363(C) |
申请公布日期 |
2005.04.12 |
申请号 |
CA19942123363 |
申请日期 |
1994.05.11 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
FIRESTONE, RAYMOND A.;DUBOWCHIK, GENE M. |
分类号 |
A61K9/00;A61K31/19;A61K38/00;A61K39/385;A61K39/395;A61K47/48;A61P35/00;C07K5/02;C07K5/06;C07K5/065;C07K5/087;C07K14/42;C07K14/485;C07K14/495;C07K14/52;C07K14/54;C07K14/55;C07K14/575;C07K14/595;C07K14/62;C07K14/65;C07K16/00;C07K19/00;C12N9/50;(IPC1-7):C07K19/00;C07K9/00;C07K5/04;C07K7/04;C07K1/107;C07K14/435 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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