| 发明名称 |
ГЕТЕРОАРИЛСОЕДИНЕНИЯ, ПОЛЕЗНЫЕ В КАЧЕСТВЕ ИНГИБИТОРОВ GSK-3 |
| 摘要 |
The present invention relates to compounds of formula I useful as inhibitors of GSK-3 and Lck protein kinases. The present invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of utilizing those compositions in the treatment and prevention of various disorders, such as diabetes, Alzheimer's disease, and transplant rejection. |
| 申请公布号 |
RU2004126671(A) |
申请公布日期 |
2005.04.10 |
| 申请号 |
RU20040126671 |
申请日期 |
2003.02.06 |
| 申请人 |
ВЕРТЕКС ФАРМАСЬЮТИКАЛЗ ИНКОРПОРЕЙТЕД (US) |
发明人 |
ХАРБЕСОН Скотт Л. (US);ЭРНОСТ Майкл Дж (US);ГРИН Джереми (US);САВИК Владимир (GB) |
| 分类号 |
C07D235/18;A61K31/4184;A61K31/4245;A61K31/437;A61K31/4427;A61K31/4439;A61K31/501;A61K31/506;A61K31/519;A61K31/52;A61K31/5377;A61P3/10;A61P9/00;A61P9/10;A61P11/06;A61P17/14;A61P25/00;A61P25/14;A61P25/16;A61P25/18;A61P25/28;A61P37/08;C07D401/04;C07D403/04;C07D409/04;C07D413/04;C07D413/14;C07D471/04;C07D487/04 |
主分类号 |
C07D235/18 |
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