| 摘要 |
FIELD: immunology, pharmacology. ^ SUBSTANCE: the suggested composition includes virion anti-herpetic preparation that contains viruses of herpes simplex of 1 or 2 serotypes inactivated either with formalin or gamma-radiation, moreover, the composition mentioned is supplemented with immunomodulator polyoxidonium; composition in question additionally contains valine and lysine and, also, the combination consisting of not less than 2 amino acids chosen out of the group of: phenylalanine, leucine, alanine, threonine, histidine, arginine, methionine at a certain ratio of components. The composition may additionally contain albumin and some vitamins. Another objective of the present innovation is the method to prepare a suppository based upon this pharmaceutical composition that includes mixing active components and cacao oil according to standard technique, moreover, as an active substance one should add the above-mentioned pharmaceutical composition and either one or several microelements chosen out of the following group: zinc, chromium, selenium and nickel. The innovation enables to keep antigenicity and stability of specific activity of the preparation mentioned along with enhanced antiviral properties; moreover, body resistance is increased and prolonged both in case of acute and chronic infection. New medicinal form of the composition suggested is easy for application. ^ EFFECT: higher efficiency of application. ^ 6 cl, 4 ex, 2 tbl |
