发明名称 |
ЛЕКАРСТВЕННАЯ ФОРМА, СОДЕРЖАЩАЯ ТЕРАПЕВТИЧЕСКОЕ СРЕДСТВО И СРЕДСТВО С ПОБОЧНЫМ ЭФФЕКТОМ |
摘要 |
The present invention provides an oral dosage form comprising a first composition and a second composition. The first composition comprises an effective amount of a therapeutic agent and the second composition comprises an effective amount of an adverse-effect agent. The adverse-effect agent is covered with a coating that is substantially insoluble in the gastrointestinal tract. In one embodiment, the adverse-effect agent is coated with an outer base-soluble layer and an inner acid-soluble layer. The therapeutic agent can be uncoated or can be coated with a coating having an outer acid-soluble layer and an inner base-soluble layer. The dosage form discourages administration of the therapeutic agent by other than oral administration. |
申请公布号 |
RU2004106620(A) |
申请公布日期 |
2005.04.10 |
申请号 |
RU20040106620 |
申请日期 |
2002.08.05 |
申请人 |
ЭРО-СЕЛТИК, С.А. (LU) |
发明人 |
РАЙТ Кертис IV (US);КАРПАНЦО Энтони Е. (US) |
分类号 |
A61K9/16;A61K9/20;A61K9/28;A61K9/30;A61K9/50;A61K9/54;A61K31/485;A61K45/06;A61P25/04 |
主分类号 |
A61K9/16 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|