СПОСОБ ЭКСПРЕССИИ БЕЛКОВ, СОДЕРЖАЩИХ В КАЧЕСТВЕ КОМПОНЕНТА ГИБРИДНЫЙ ИЗОТИП АНТИТЕЛА

摘要

Disclosed are methods and compositions for efficiently expressing antibody fusion proteins. Antibody fusion proteins of the invention include a hybrid antibody moiety containing sequences from more than one type of antibody and/or mutant antibody sequences. Hybrid antibody fusion proteins of the invention may be produced at high levels and may combine functional properties characteristic of different antibody types in addition to functional properties of a non-antibody moiety.